Expectant parents can
  • collect and preserve for the potential medicinal benefit of the family.
  • donate the blood for research or use by a third party. This is commonly referred to as the public option.
  • allow the hospital to discard it.
Cord blood and cord tissue have an abundance of stem cells that can easily be collected and cryopreserved in case they are ever needed. Stem cell treatments and transplants have already been used for a wide range of diseases and conditions such as cancers (including lymphoma and leukemia) and inherited metabolic disorders. In addition, research for future uses of stem cells in the treatment of diabetes, Alzheimer’s, autism and cerebral palsy holds great promise.

Follow the link to learn more about how cord blood and cord tissue compare.
Approximately nine of every 10 cord blood samples donated to a public bank are discarded. If your baby needs a stem cell transplant, finding a match through public cord blood banks is not a guarantee, and odds are even lower for certain ethnicities. The retrieval process and necessary testing to ensure candidates are a proper match can take valuable weeks, even months, to perform. Retrieving a match from a public bank is also expensive. The current average cost is $40,000 for retrieval from a public cord blood unit.

Follow the link to learn more about the differences between public and private banking.
Cord blood stem cells have a number of significant advantages over other sources of stem cells (e.g., bone marrow):
  • Higher rate of engraftment
  • More tolerant of tissue mismatches
  • Lower rate of severe graft-vs.-host disease (a major complication in stem cell transplants)
  • Less likely to be contaminated with latent viruses
  • Easier to collect in some cases
In addition, cord blood is "privileged," or unexposed to most diseases, which can make bone marrow from an adult more difficult to use in transplantation. Most importantly, cord blood from your baby is a perfect match for your child, in the unlikely event it should ever be needed, and has a 75 percent chance of being an acceptable match for any siblings. It is important to note that a perfect match may not imply that the cells would be useful to treat certain diseases of the donor.

Follow the link to learn more about how cord blood and cord tissue stem cells have more benefits than similar stem cells from other sources.
Umbilical cord blood was first used for transplantation in France in 1988 for a patient with Fanconi's anemia; a disease-free sibling was the donor. Since that time, cord blood has become a standard alternative to bone marrow and has been used in more than 35,000 successful transplants (33% of which were for patients age 18 or younger).

We have had many successful cord blood transplants for diseases including leukemia, anemia and lymphoma. Please see our treating diseases section and our transplant matrix for specific diseases treated with cord blood from Cryo-Cell.
The nature of treatments for many diseases has changed radically over the past several years. As the causes of more diseases are determined, more therapies will become available, and it is projected that cord blood transplantation will continue to play a vital role in these therapies. Current promising research is being conducted on the use of umbilical cord blood stem cells for the treatment of many diseases including those of the cardiovascular and nervous systems.

Learn more about the future of stem cells in our blog or Stem Cell Insider newsletter.
Until the child is of legal age, the parents, as the child's guardians, have control over the stem cells. No stem cells will be released by us without the parents' consent. Once they reach legal age, the child's consent will be needed.

The preserved cord blood stem cells are a perfect match for the lifetime of the donor, and have a 75 percent chance of being a match for siblings who share the same mother and father. In fact, approximately half of stem cells transplants from us have gone towards siblings. Statistics show that there is a greater chance for success in a stem cell transplant between siblings than with unrelated donors. There is also a reduced likelihood of graft-versus-host disease (GVHD), which is a major complication of stem cell transplants. If you are planning on having additional children, we strongly suggest you consider this once-in-a-lifetime opportunity.

In addition to siblings, a donor’s stem cells could potentially be useful to other family members who may need them, including the mother or father.
Since you own the preserved cord blood or blood and tissue, there is no charge for retrieval. If retrieval is requested, your collection will be transported in a special container to the transplant location in order to maintain cryogenic temperatures. You would be responsible for the cost of transportation.
Cord blood and tissue are collected immediately after either vaginal birth or cesarean section delivery. Since a collection kit is necessary at the time of birth, advance arrangements must be made.

Umbilical cord blood is easily collected by your caregiver using the umbilical cord blood and cord tissue collection kit and instructions supplied therein. The umbilical cord is clamped and cut in the same manner as it would be for normal delivery of the baby. Using a cord blood collection bag, the staff will draw blood from the umbilical cord. Our cord blood collection bag is sterile inside and out and is the only type of bag that has been approved by the Food and Drug Administration (FDA) and as a New Drug Application (NDA). We also use a heparin-free collection process that maximizes stem cell recovery.

Cord tissue is collected after the cord blood has been collected and the placenta has been delivered. A 4”–8” segment of the cord is cleansed and cut to place in a container for transport to the laboratory. The container will be transported along with the cord blood for immediate processing.

The cord blood and, if applicable, tissue are packaged with the mother's blood sample in the special shipping materials provided in the kit. A medical courier will personally pick up your collection kit from your hospital room and deliver it to our facility within 24 to 48 hours, where our staff is available 24 hours a day, seven days a week to process, test, separate and cryogenically store your baby's stem cells. You may arrange for the transport of your collection kit by calling Cryo-Cell  any time at 1-800-786-7235. Once prompted, select option one. The courier will schedule the pick-up of your collection kit. The kit should be kept at room temperature prior to transport.

Folow the link to learn more about the banking process.
There is absolutely no pain or risk to the mother or child during the collection process because the blood is harvested from the cord once it has been clamped and cut.

Learn more about the banking process.
Parents who wish to store their baby’s cord blood may still delay cord clamping. Because of the delay in clamping, a smaller volume of cord blood will be collected; therefore, the efficacy of the cord blood processing method is extremely important. A defining study published in the International Journal of Stem Cells examined different processing technologies (i.e., the means by which the stem cells are separated out from the blood). According to the study, PrepaCyte CB processing is “the only processing type unaffected by volume”; therefore, it is the best processing option for cords collected after the delayed-clamping procedure to preserve the most cells as possible. We are the only private cord blood bank that offers PrepaCyte CB processing.

Learn more about PrepaCyte-CB.
We perform the following tests on every collection kit:
  • Maternal blood is tested for syphilis, hepatitis B and C, human T-lymphotropic virus (HTLV), human immunodeficiency virus (HIV), Chagas disease, West Nile virus and cytomegalovirus (CMV).

    In the event that any of the infectious disease screening tests are positive, confirmatory tests will be automatically performed. Infectious disease testing is performed by an affiliated laboratory that is Clinical Laboratory Improvement Amendments (CLIA)–certified and FDA-registered. The testing regimen outlined allows the sample to be considered for use on other family members (e.g., siblings) in addition to the baby whose cord blood was collected.

    Human leukocyte antigen (HLA)–typing is not routinely performed at the time of processing but would be necessary to confirm the compatibility between the donor and a recipient of the cells if they are different. If HLA-typing is necessary in the future, it may be performed via blood testing as an insurance reimbursable cost in a typical physician-ordered transplant plan.

  • Each cord blood sample is also tested for microbiological contamination.
Any blood found to be positive for a communicable disease or infection is placed in quarantine.

Follow the link to learn more about our cryopreservation/banking process.
There are 2 options for cord blood processing. The hydroxyethyl starch (Hetastarch®) method reduces the number of red blood cells and isolates the nucleated white blood cell fraction, which contains the stem cells. These cells are then mixed with dimethyl sulfoxide (DMSO), a cryoprotectant, and Dextran and stored in a special compartmentalized cryo-bag.

Cryo-Cell’s proprietary PrepaCyte-CB® processing system is more advanced and returns a higher, cleaner yield. It is especially beneficial in delayed-cord clamping. Follow the link to learn more about PrepaCyte-CB.

​We use a forward-looking five-compartment storage cryo-bag. The bag includes five detachable compartments as well as segments for testing. (Follow to learn more about how our five-compartment cryo-bag is preparing families for the future.) Our cryo-bag is over-wrapped for added protection and undergoes a technique called "controlled-rate freezing," which helps prepare the cells for long-term storage. Then, the bag is housed in a protective metal cassette and placed in liquid nitrogen freezer for cryogenic preservation.

Learn more about how cord blood is processed.

Cord tissue is treated with a buffered solution to clean the cord when it arrives in the lab. The cord is then processed into pieces to cryogenically store the tissue and cells. The cryopreserved tissue is stored in two (2) containers. To enhance the safety of the stored materials, they are over wrapped and the containers are stored in the vapor phase of liquid nitrogen.
We have our own state-of-the-art, secure laboratory in Oldsmar, Florida, where the cord blood and, if applicable, tissue are processed and stored. They are housed in a bunker rated for a category 5 hurricane and have electrical and other backup systems in place to ensure long-term safety. Storage conditions are constantly monitored for security and temperature.

Learn more about our facility and laboratory.
Sufficient years have not passed to prove the absolute length of time; however, it is believed that stem cells can be successfully stored long term in a cryopreserved form. A recent study of cord blood at Indiana University demonstrated its viability after 23.5 years of cryogenic storage. Bone marrow has been stored for decades and has remained viable; there is no reason to believe that the same would not be true of cord blood.

Learn about a study that looked at the effects of long-term cryo-preservation on cord blood.
We strive to make cord blood and tissue banking accessible to everyone. We lump our processing and testing fees together to cover the entire upfront costs including enrollment, the collection kit, outbound kit shipping, the medical courier, and the first year of storage. Infectious disease screening tests are also included for the birth mother's blood. Prices are for a single child. 

The storage fee is fixed for the 18 years and will not increase during that span of time. If the cells are preserved after the 18th year, preservation may then fall under the new pricing structure. 

We have 12- and 24-month in-house payment plans to spread the initial cost out over time. They require no credit check and begin with little money down. We also offer discounts for returning clients, multiple children, retired and active military and medical professionals and special pricing for people who take advantage of our 21-year storage plan. 

We offer collections kits free of any charges so long as they are timely returned after deciding not to enroll. Refunds on upfront costs are not available after we have received and processed the collection. Annual plans may choose to cancel preservation at the time of renewal. If testing shows the collection is suboptimal, we will contact you regarding your options. 

To learn more about our pricing, payment plans, and discounts, follow the link to our pricing page.
Many healthcare providers charge a fee for collecting umbilical cord blood. We suggest that you discuss this procedure with your healthcare provider prior to enrolling in our service to verify their agreement to perform the collection.
Founded in 1989, we were the first private cord blood bank to isolate and store stem cells. We now serve more than 500,000 parents worldwide through our highly trained staff and the company’s state-of-the-art laboratory operations. 

We are a publicly traded company. Day-to-day operations are performed by the Co-CEOs David and Mark Portnoy. In the pursuit of improvements to our current products and the creation of new products, we have become associated with Saneron CCEL, a University of South Florida spin-out, as well as other research and development institutes. We have also established an affliate network to provide our services abroad. All services, such as blood testing, are performed in conjunction with our cord blood and tissue service. 

Follow the link to learn more about Cryo-Cell.
In May 2005, the U.S. Food and Drug Administration (FDA) began regulating family cord blood banks. Beyond the federal government, several states (California, Illinois, New York, New Jersey and Maryland) have applicable regulations. In addition to these government requirements, several organizations offer accreditation for cord banks that meet their standards.

Our list of accreditations include
  • FDA-registered
  • cGMP-/cGTP-compliant
  • Licensed in all states requiring such (California, Illinois, New York, New Jersey and Maryland)
  • AABB-accredited
  • FACT-accredited
  • ISO 13485:2008-certified
Our list of licenses and accreditations makes Cryo-Cell one of the recognized quality leaders in the field. Follow the link to read more about our licenses and accreditation.
Follow the link to enroll today. The enrollment process takes 10 minutes to complete and just involves providing us with some information about you and your healthcare provider. No fees will be charged until the date we receive your sample unless you sign-up for one of our payment plans.

You can also enroll over the phone by calling us any time day or night. We are always available at 1-800-STOR-CELL (1-800-786-7235). Your kit will be shipped to you immediately upon enrollment.

For parents ordering the kit within 30 days of the expected due date, or for any situation that requires the kit more quickly than the standard delivery service, we offer expedited (overnight) delivery service via our medical courier service to U.S. and Puerto Rico clients.

Upon arrival
  • Store our advanced collection kit at room temperature at all times to avoid exposure to temperature extremes. Do not leave the kit in your car. The kit includes dual temperature gauges. If they report exposure to extreme hot or cold conditions, the collection will have to undergo additional testing to ensure they are optimal.
  • Read through all the printed material included with the kit so that your questions may be answered before you arrive at the hospital or birthing center.
  • Complete the top portion of the Parent Information Collection Sheet.
  • Review the labeling, packaging and shipping instructions in the parent instructions.
  • Make sure to take the kit and all paperwork to the hospital or birthing center when it’s time to deliver your baby.
The call you place to our transportation coordinator is the only notification we need after the birth of your baby; we will handle the rest for you! Our transportation coordinator will obtain a tracking number when scheduling the transportation of your specimen, which enables us to track its delivery. Our transportation coordinator will follow up with a phone call to provide you with confirmation of receipt.
Within four to six weeks of processing, testing and storing, you will be provided with written confirmation of lab results and a certificate of preservation with the information about the baby and what was collected including the volume processed, white blood cell count, CD34+ cell count and ABO type. If testing shows the collection falls short for any of our set critieria, we will contact you regarding the results and your options.
As a Cryo-Cell International client, you will receive updates via mail and email about breakthroughs and discoveries in the field and how we are helping people around the globe. Follow the link to request e-mail updates without enrolling. You can also visit our website to read the latest news from our Stem Cell Insider newsletter center and the Cryo-Cell blog.