Recently, there has been a proliferation of start-up companies to cryogenically preserve the blood of adults for future use. These companies have come under recent scrutiny after the International Society of Cell & Gene Therapy (ISCT) issued a consumer alert. What did the ISCT determine? In a nutshell, storing adult stem cells for future use is unwise. We support the ruling of the Food and Drug Administration (FDA) and ISCT’s stance. Let’s address the what, how, and why.