Expectant parents can:
 Collect and preserve the cells for the potential future medical benefit of the family
 Donate the blood for research or use by an unrelated third party
 Allow the hospital to discard the newborn's blood
Since cord blood has an abundance of stem cells, the can easily be collected and cryopreserved in case they are needed later in life. Stem cell treatments and transplants have already been used for a wide range of diseases and conditions such as cancers (including lymphoma and leukemia) and inherited metabolic disorders. Research for future uses of stem cells, such as the treatment of diabetes, Alzheimer’s and cerebral palsy, holds great promise. Often, matched stem cells necessary for transplants are difficult to obtain through public cord blood banks; however, cells taken from your newborn’s umbilical cord blood are a perfect match for your baby for a lifetime and a probable sibling match. In addition, stem cell technologies are evolving, which is likely to increase the utilization of preserved specimens in the future.
Statistics show that there is a greater chance for success in a stem cell transplant between siblings than with unrelated donors and recipients. There is also a reduced likelihood of Graft-versus-Host Disease (GVHD), which is a major complication of stem cell transplants. If you are planning on having additional children, we strongly suggest you consider this once-in-a-lifetime opportunity.
As parents, we want so very much to protect our children from all the dangers in the world; it is a privilege to be able to add this element of protection against some of the most devastating possibilities our children might face in their lifetime. Each family makes financial decisions with its own set of values and competing needs and wants. However, our clients tell us that they look back on their decision to store their baby's umbilical cord blood stem cells as one of the most rewarding decisions they've made. We see this in a very tangible way with the very high number of our repeat clients.

At Cryo-Cell, we adhere to the highest standards of quality.

With the increasingly promising research revealing the potential of future stem cell therapies for cardiac disease or neurological diseases, we believe that the value for the cost of collection and preservation of cord blood is increasing every day.
Cryo-Cell strives to make cord blood and cord tissue banking affordable. The Processing and Testing Fee covers the cost of enrollment, the collection kit, outbound kit shipping and medical courier. Infectious disease screening tests are also included for the birth mother's blood. The medical courier included fees only apply to U.S. and Puerto Rico clients. Cryo-Cell offers special pricing for returning clients and multiples, as well as a 21-year Storage Plan. For complete details on our fee structure and payment plans, click here.
Cryo-Cell is one of the oldest and largest family cord blood stem cell banks. We were incorporated in 1989 and have been involved in the umbilical cord blood preservation business since 1992. Cryo-Cell is a publicly traded company (OTC: QB Markets Group Symbol: CCEL) specializing in stem cell cryopreservation. We have a state-of-the-art processing lab and cryogenic storage facility in Oldsmar, Florida. Our facility is cGMP/cGTP-compliant.
Cryo-Cell is committed to providing superior customer service and the highest quality standards for its cord blood service. We were the first private cord blood bank to isolate and store stem cells and are one of the world's largest, serving over 240,000 worldwide clients.  Cryo-Cell’s mission is to provide our clients with the premier stem cell cryopreservation service and to support research and development initiatives for regenerative medicine.
Cryo-Cell is one of the industry’s quality leaders.  Our associates are highly trained and the Company’s state-of-the-art laboratory operation utilizes high quality equipment and manufacturing processes to process, test and preserve your baby's cord blood stem cells. Oversight of our service is provided by the Company’s impressive Medical & Scientific Team. Our Client Services Department includes a team of highly trained advisors and nurse practitioner who are available to assist you with questions 24/7.
Cryo-Cell is a publicly-traded company governed by the United States Securities and Exchange Commission. Our financial information is audited by a nationally recognized independent accounting firm and is available to the public.
Umbilical cord blood is the blood that remains in the vein of the umbilical cord and placenta at the time of birth. Cord blood is rich in stem cells and Cryo-Cell’s umbilical cord blood service collects, processes and cryogenically preserves these cells for potential medical use. Umbilical cord blood stem cells have been used to treat nearly 80 diseases with over 25,000 transplants worldwide.
Cord blood stem cells have a number of significant advantages over other sources of stem cells (i.e., bone marrow):

 Cord blood has a high rate of engraftment
 More tolerant of tissue mismatches
 Results in a lower rate of severe Graft-vs-Host disease (a major complication in stem cell transplants)
 Rarely contaminated with latent viruses
In addition, cord blood is "privileged" or unexposed to most diseases, which can make bone marrow from an adult more difficult to use in transplantation. But most importantly, cord blood from your baby is a perfect match for your child, in the unlikely event it should ever be needed, and has a 1-in-4 chance of matching a current or future sibling. It is important to note that a perfect match may not imply that the cells would be useful to treat certain diseases of the donor.
Cord blood is collected from the umbilical cord immediately after the birth of the baby, and can be performed with either vaginal or cesarean section deliveries. The collection can only take place at the time of delivery, and, since a collection kit is necessary, advance arrangements must be made. There is absolutely no pain or risk to the mother or child during the collection process since the blood is harvested from the cord once it has been clamped and cut.
Umbilical cord blood is easily collected by your caregiver using the umbilical cord blood and cord tissue collection kit and instructions supplied by Cryo-Cell. The umbilical cord is clamped and cut in the same manner as it would be for normal delivery of the baby. Using a cord blood collection bag, blood is drawn from the umbilical cord. Cryo-Cell’s cord blood collection bag is the only bag, which is FDA & NDA approved and we use a Heparin-free collection process using CPD, which maximizes stem cells recovery.
Many healthcare providers charge a fee for the procedure of collecting umbilical cord blood. We suggest that you discuss this procedure with your healthcare provider prior to enrolling in our service to verify their agreement to perform the collection.
The cord blood is packaged with the mother's blood in the special shipping materials provided in the kit. Cryo-Cell has a special agreement with a medical courier to pick up your specimen(s) from your hospital room and deliver it to our facility within 24 to 48 hours of collection, where it is processed, tested, separated and the stem cells are cryogenically stored. You may arrange for the transport of your specimen by simply calling a Cryo-Cell Transportation Coordinator 24/7 at 1-800-786-7235, option 2. Cryo-Cell provides you a medical courier at a flat rate fee1, 2 who will assist you with scheduling the pick-up of your specimen(s).  The specimen(s) should be kept at room temperature prior to transport.
Cryo-Cell has its own state-of-the-art laboratory in Oldsmar, Florida where the Cord blood is processed and stored. Cryo-Cell is registered with the FDA, accredited by the AABB and ISO 9001:2008 certified. Cryo-Cell specializes in cord blood processing and storage and is one of the pioneers in the commercial storage of separated cord blood cells.
Cryo-Cell Stem Cell Bank currently uses a hydroxyethyl starch (Hetastarch®) method to reduce the number of red blood cells, isolating the nucleated white blood cell fraction, which contains the stem cells. These cells are then mixed with DMSO, the cryoprotectant, and Dextran, and stored in a special compartmentalized cryobag.
Cryo-Cell performs the following tests on every specimen:
 Maternal blood is tested for syphilis, hepatitis, HTLV, HIV and CMV. This testing regimen determines the infectious disease status and allows the cord blood to potentially be used for "family use", not just "autologous (self) use." In the event that any of the infectious disease screening tests are positive, confirmatory tests will be automatically performed. The cost for the initial screening tests are included in Cryo-Cell's fee; the costs for confirmatory testing, if required, will be billed separately and will typically be less than $100.00.
 Each cord blood sample is also tested for the absence of microbiological contamination.
Infectious disease testing is performed by an affiliated laboratory that is CLIA certified and FDA registered. The testing regimen outlined allows the sample to be considered for use on other family members, (i.e., siblings) in addition to the baby whose cord blood was collected. HLA typing is not routinely performed at the time of processing, but would be necessary to confirm the compatibility between the donor and a recipient of the cells if they are different. If HLA (human tissue) typing is necessary in the future, it may be performed via blood testing as an insurance reimbursable cost in a typical physician ordered transplant work-up.
Cryo-Cell currently stores the cord blood cells in a compartmentalized cryobag. The bag includes a 20ml and 5ml sample, three segments for testing and is over-wrapped for added protection. A technique called "controlled-rate freezing" is used to prepare the cells for long-term storage. Then, the bag is housed in a protective cassette and placed in liquid nitrogen dewars for cryogenic preservation. Our storage conditions are monitored for security and temperature.
Until the child is of legal age, the parents, as the child's guardians, have control over the stem cells. No stem cells will be released by Cryo-Cell without the parents' consent initially, and later the child's consent, once they reach legal age.
The preserved cord blood stem cells are, of course, available as a perfect match for the child from whose umbilical cord they were collected. Because there is a 1-in-4 chance of a perfect match with a sibling, parents may choose to make the cord blood available to siblings or potentially other family members who may need them.
Since you own the preserved specimen, there is no charge for retrieval. The specimen would be transported in a special container, to the transplant location, in order to maintain cryogenic temperatures. You would be responsible for the cost of transportation.
Umbilical cord blood was first used for transplantation in 1988, in France, for a patient with Fanconi's anemia; a disease-free sibling was the donor. Since that time, cord blood has been increasingly used as a substitute for bone marrow in 25,000 successful transplants.
Cord blood stem cells may be used in place of bone marrow or other sources of stem cells for transplantation and has already been used to treat numerous types of malignancies including certain leukemia's, Hodgkin's disease and other types of lymphoma. It has also been used for the treatment of a variety of anemias, inherited metabolic disorders and deficiencies of the immune system. The majority of cord blood transplants, to date, has been performed in patients less than 18 years old and has been sibling or allogeneic (unrelated third party) transplants. Click here to view diseases treated
Cord blood transplants have been demonstrated to be at least as successful as bone marrow in the cases in which they have been used. By comparison, cord blood has other advantages over bone marrow, including ease of collection and better tolerance of HLA mismatches.
Cryo-Cell has had a number of successful cord blood transplants for diseases including leukemia, anemia and lymphoma. Please see our treating diseases section of our website and our transplant matrix for specific diseases treated with cord blood from Cryo-Cell.
The nature of treatments for many diseases has changed radically over the past several years.  As the causes of more diseases are determined, more therapies will become available, and it is projected that cord blood transplantation will continue to play a vital role in these therapies. Current promising research is being conducted on the use of umbilical cord blood stem cells for the treatment of many diseases, including cardiac and neurological.
Sufficient years have not passed to prove the absolute length of time; however, it is believed that stem cells can be successfully stored long term, perhaps decades, in a cryopreserved form. A recent study of cord blood at Indiana University demonstrated its viability after 23.5 years of cryogenic storage. Bone marrow has been stored for decades and has remained viable; there is no reason to believe that the same would not be true of cord blood.
 You can enroll online by providing us with information about yourself and your healthcare provider. The enrollment process takes 10 minutes to complete.
 You can also enroll over the phone by calling us at your convenience and in the comfort of your surroundings -- any time of day or night, 24/7. We are always available at 1-800-STOR-CELL (1-800-786-7235).
 Your kit will be shipped to you immediately upon enrollment.
 For parents ordering the kit within 30 days of the expected due date, or for any situation that requires the kit more quickly than the standard delivery service, Cryo-Cell offers an expedited (overnight) delivery service via Cryo-Cell’s medical courier service to U.S. and Puerto Rico clients.1,2
 Store the kit at room temperature at all times to avoid exposure to temperature extremes. Do not leave the kit in your car.
 It is very important that you read through all the printed material included with the kit as soon as you receive it so that your questions may be answered before you arrive at the hospital or birthing center.
 Complete the top portion of the Parent Information Collection Sheet.
 Review the labeling, packaging and shipping instructions in the Parent Instructions.
 Make sure to take the kit and all paperwork to the hospital or birthing center when it’s time to deliver your baby.
For optimal viability results we highly recommend that your specimen is received in our laboratory within 24 to 48 hours of collection.
The call you place to Cryo-Cell’s Transportation Coordinator is the only notification we need after the birth of your baby; we will handle the rest for you! Our Transportation Coordinator will obtain a tracking # when scheduling the transportation of your specimen, which enables Cryo-Cell to track the delivery of your specimen. Our Transportation Coordinator will follow up with a phone call to provide you with confirmation of receipt, and you will be provided with written confirmation of lab results within four-to-six weeks of processing, testing and storage.
Umbilical cord blood is the blood that remains in the umbilical vein in the umbilical cord and placenta at the time of birth. This blood is rich in hematopoietic or blood derived stem cells. The cord tissue or Wharton’s jelly is the tissue surrounding the umbilical vein and vessels in the cord. When the vessels are removed you have tissue remaining which contains stem cells termed mesenchymal stem cells. The mesenchymal stem cells have the capability to differentiate into bone cells, fat cells and cartilage to name a few. The tissue is very rich in these stem cells.
After the cord blood has been collected and the placenta has been delivered, the cord tissue will be collected. A 4-8” segment of the cord is cleansed and cut to place in a container for transport to the laboratory. The cord tissue collection is safe and may be collected in both a vaginal and cesarean section births. The container will be transported along with the cord blood for immediate processing once it reaches the laboratory.
The cord tissue will be discarded if you do not select the option to store the cord tissue.
The cord tissue is treated with a buffered solution to clean the cord when it arrives in the lab. The cord is then processed into pieces to cryogenically store the tissue and cells. The cryopreserved tissue is stored in two (2) containers. To enhance the safety of the stored specimens they are over wrapped and the containers are stored in the vapor phase of liquid nitrogen.
Additional fees will be required to prepare the cells for use when the need arises.
The client will also be responsible for any additional testing required and transportation fees.
The cells have been assessed in pre-clinical studies for multiple diseases including acute kidney injury, spinal cord injury, retinal disease, blood vessel repair, nerve regeneration, heart disease and stroke. Peer-reviewed journal references are available upon request
Mesenchymal stem cells from many different tissues are being tested in clinical trials for efficacy. In addition, cells specifically derived from cord tissue are currently being used in several clinical trials, for example, treating Cardiomyopathy, Ulcerative Colitis, Diabetes, Anemia, Autism and Cirrhosis of the Liver. For more information on these clinical trials you may log on to clinicaltrials.gov.