Getting Closer to a Stem Cell Therapy for Parkinson's Disease

HSCI scientists have developed new ways to identify, grow, sort, and transplant the dopamine-producing cells that are lost in Parkinson’s disease. Additionally, they have learned how to identify and remove unwanted cells prior to transplantation, such as cells that produce cerebrospinal fluid.

HSCI Principal Faculty member Ole Isacson, MD, and colleagues tested their new methodologies by using skin cells from primates to create dopamine-producing neurons, which they could isolate from the surrounding background cells, and implant into the brains of the animals.

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